• Based on BASF’s patented solid lipid encapsulation technology to stabilize retinol in cosmetic formulations
• Benefits of retinol encapsulation counters known drawbacks such as irritation and stability
• Delivers proven anti-ageing benefits, including visible improvement of forehead wrinkle appearance

Hong Kong SAR, China – January 23, 2025 – BASF’s Personal Care business is launching a new ingredient, VitaGuard® A to capture the continuous market demand for retinol, while reinforcing its position as a Hero ingredient in cosmetics. This latest innovation is based on the encapsulation of free retinol. Retinol is a powerful anti-aging molecule widely used in cosmetic applications. However, it can also cause skin irritation and is prone to light and air degradation, making it difficult to be widely utilized by formulators. VitaGuard® A was developed using patented solid lipid particles, protecting retinol from degradation, limiting skin irritation and allowing better skin bioavailability for improved cosmetic efficacy.

Several in vitro and ex vivo studies conducted by BASF have shown VitaGuard® A to improve retinol stability in cosmetic formulations compared to non-encapsulated retinol, enhance skin bioavailability and prevent retinol-induced irritation. Additionally, it clinically improves the forehead wrinkles appearance, skin elasticity and skin tone evenness to connect with retinol’s attractive nature as an anti-aging molecule.

Clinical study conducted with VitaGuard® A on its effectiveness as an anti-aging molecule

In a randomized, full-face, double-blind clinical study on Chinese volunteers, VitaGuard® A as a cream was evaluated at 2% (equivalent to 0.1% retinol) on its effectiveness as an anti-aging molecule compared to non-encapsulated retinol at 0.1%. The results concluded that VitaGuard® A significantly showed an anti-wrinkle effect on forehead wrinkle appearance compared to baseline (D0). After 8 weeks, forehead wrinkle volume was reduced by 37% (p<0.01). While assessing skin elasticity improvement, compared to baseline, VitaGuard® A showed significant increase in skin elasticity vs D0 (+16%, p<0.001). Moreover, skin tone evenness was notably improved, showing a variation of 15% compared to the baseline measurements obtained (p<0.001). All these parameters were found to be directionally better versus the same formulation containing non-encapsulated retinol at the same dose of 0.1%.

The development of VitaGuard® A highlights BASF’s commitment to addressing customers’ needs for the ease of use of retinol, while delivering notable anti-aging effects. Furthermore, it is an example of how the company’s Personal Care business is addressing future challenges. Sustainability, digitalization, innovation and new approaches to working together are the key cornerstones to Care 360° – Solutions for Sustainable Life.